4-Methoxy-1-vinyl-β-carboline, a new alkaloid from Picrasma javanica (Simaroubaceae)
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Isolation and in vitro antimalarial activity of chloroform extract from Thai Picrasma javanica Bl stembark
The in vitro antimalarial activity against Plasmodium falciparum K1 of the four extracts from the stembark of Picrasma javanica Bl, that is, water, methanol, chloroform and hexane were studied using a modification of the [ 3 H]hypoxanthine incorporation method. It was found the chloroform extract showed in vitro antimalarial activity with IC50 of 20.0 g/ml. The extract was further isolated usi...
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During further chemical and biological investigations of Picrasma quassioides BENNET, four new bis-β-carboline alkaloids, quassidines E-H (1-4), and three new β-carboline alkaloids, canthin-16-one-14-butyric acid (5), 3-(1,1-dimethoxylmethyl)-β-carboline (6), and 6,12-dimethoxy-3-formyl-β-carboline (7), were isolated from its anti-inflammatory CHCl(3)-soluble fraction. Structures of new compoun...
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ژورنال
عنوان ژورنال: Australian Journal of Chemistry
سال: 1970
ISSN: 0004-9425
DOI: 10.1071/ch9700629